Hung-Ying Kao Selected Research

Promyelocytic Leukemia Protein

1/2018	PML: Regulation and multifaceted function beyond tumor suppression.
1/2015	The function, regulation and therapeutic implications of the tumor suppressor protein, PML.
8/2014	Control of antioxidative response by the tumor suppressor protein PML through regulating Nrf2 activity.
10/2013	Ablation of promyelocytic leukemia protein (PML) re-patterns energy balance and protects mice from obesity induced by a Western diet.
9/2012	Microarray analysis revealing common and distinct functions of promyelocytic leukemia protein (PML) and tumor necrosis factor alpha (TNFα) signaling in endothelial cells.
7/2012	Promyelocytic leukemia protein (PML) regulates endothelial cell network formation and migration in response to tumor necrosis factor α (TNFα) and interferon α (IFNα).
1/2012	Post-translational modifications of PML: consequences and implications.
3/2010	Promyelocytic leukemia protein controls cell migration in response to hydrogen peroxide and insulin-like growth factor-1.
9/2009	PML: An emerging tumor suppressor and a target with therapeutic potential.
5/2009	Targeting promyelocytic leukemia protein: a means to regulating PML nuclear bodies.

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Hung-Ying Kao Research Topics

Disease

14	Neoplasms (Cancer) 05/2020 - 09/2009
6	Breast Neoplasms (Breast Cancer) 01/2013 - 04/2009
4	Kidney Diseases (Kidney Disease) 01/2018 - 04/2012
4	Acute Promyelocytic Leukemia 01/2018 - 09/2009
4	Proteinuria 01/2018 - 04/2012
3	Genetic Translocation (Chromosomal Translocation) 01/2018 - 03/2010
3	Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal) 01/2017 - 04/2012
3	Inflammation (Inflammations) 08/2013 - 07/2012
3	Virus Diseases (Viral Diseases) 12/2011 - 02/2008
2	Carcinogenesis 05/2020 - 01/2013
2	Mouth Neoplasms (Oral Cancer) 05/2020 - 09/2019
2	Head and Neck Neoplasms (Head and Neck Cancer) 05/2020 - 09/2019
1	Lymphatic Metastasis 05/2020
1	Melanoma (Melanoma, Malignant) 01/2018
1	Nephrotic Syndrome (Syndrome, Nephrotic) 01/2018
1	Prostatic Neoplasms (Prostate Cancer) 03/2016
1	Adenocarcinoma 03/2016
1	Chronic Renal Insufficiency 01/2015
1	Rickets (Rachitis) 01/2015
1	Familial Hypophosphatemic Rickets (X-Linked Hypophosphatemia) 01/2015
1	Insulin Resistance 10/2013
1	Obesity 10/2013
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 09/2012
1	Hyperglycemia 07/2012
1	Diabetic Retinopathy (Retinopathy, Diabetic) 07/2012
1	Leukemia 12/2011
1	Colonic Neoplasms (Colon Cancer) 11/2010
1	Starvation 10/2008
1	Cardiomegaly (Heart Hypertrophy) 10/2008
1	Infections 10/2008
1	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 03/2004
1	Neurodegenerative Diseases (Neurodegenerative Disease) 03/2004

Drug/Important Bio-Agent (IBA)

12	Proteins (Proteins, Gene)FDA Link 01/2018 - 03/2004
11	Promyelocytic Leukemia ProteinIBA 01/2018 - 02/2008
4	ActininIBA 01/2015 - 01/2011
3	CytokinesIBA 08/2013 - 07/2012
3	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 09/2012 - 01/2011
2	Messenger RNA (mRNA)IBA 09/2019 - 03/2016
2	LigandsIBA 09/2019 - 09/2012
2	GlucocorticoidsIBA 01/2018 - 01/2017
2	Microfilament Proteins (Actin Binding Proteins)IBA 01/2015 - 01/2011
2	Phosphotransferases (Kinase)IBA 10/2013 - 12/2011
2	Glucose (Dextrose)FDA LinkGeneric 10/2013 - 07/2012
2	Pharmaceutical PreparationsIBA 01/2013 - 07/2012
1	betaglycan (TGFBR3)IBA 05/2020
1	angiogeninIBA 05/2020
1	Angiogenesis Inducing Agents (Angiogenesis Factor)IBA 05/2020
1	NF-kappa B (NF-kB)IBA 09/2019
1	InterleukinsIBA 09/2019
1	Transcription Factors (Transcription Factor)IBA 09/2019
1	ChemokinesIBA 09/2019
1	Retinoic Acid Receptor alphaIBA 01/2018
1	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 01/2018
1	Protein Kinases (Protein Kinase)IBA 01/2018
1	AndrogensIBA 03/2016
1	MetriboloneIBA 03/2016
1	Dihydrotestosterone (Androstanolone)IBA 03/2016
1	Epidermal Growth Factor (EGF)IBA 03/2016
1	Proto-Oncogene Proteins c-fos (FRAs)IBA 03/2016
1	Vitamin D FDA LinkGeneric 01/2015
1	Calcitriol Receptors (Calcitriol Receptor)IBA 01/2015
1	Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA 01/2015
1	Adenosine Monophosphate (AMP)IBA 10/2013
1	Fatty Acids (Saturated Fatty Acids)IBA 10/2013
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2012
1	Histones (Histone)IBA 07/2012
1	Minocycline (Cyclops)FDA LinkGeneric 07/2012
1	Retinaldehyde (Retinal)IBA 07/2012
1	U 0126 (UO 126)IBA 12/2011
1	Hormones (Hormone)IBA 01/2011
1	Histone Deacetylase InhibitorsIBA 11/2010
1	Insulin-Like Growth Factor I (IGF-1)IBA 03/2010
1	Arginine (L-Arginine)FDA Link 03/2010
1	Cyclic PeptidesIBA 03/2010
1	octaarginineIBA 03/2010
1	Small Interfering RNA (siRNA)IBA 12/2009
1	Estrogen Receptor Modulators (Antiestrogen)IBA 04/2009
1	Co-Repressor ProteinsIBA 04/2009
1	Cyclin-Dependent Kinase 9IBA 10/2008
1	Positive Transcriptional Elongation Factor BIBA 10/2008
1	RNA Polymerase II (RNA Polymerase B)IBA 10/2008
1	Cyclin TIBA 10/2008
1	Matrix Metalloproteinases (MMPs)IBA 10/2008
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2008
1	Matrix Metalloproteinase 14 (MT1-MMP)IBA 10/2008
1	polyglutamineIBA 03/2004
1	RetinoidsIBA 03/2004
1	Thyroid Hormone Receptors (Thyroid Hormone Receptor)IBA 03/2004
1	Ataxin-1IBA 03/2004

Therapy/Procedure

1	Therapeutics 11/2010